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Restless Legs Syndrome

🩺 Nursing & Health By CampusDown Wiki Editorial Team Last updated
Restless legs syndrome (RLS) is a neurological condition that causes an irresistible urge to move your legs, usually in the evening or at rest, often wrecking sleep.
Contents
  1. 1. Symptoms and diagnosis
  2. 2. Causes and treatment
  3. 3. FAQ
  4. 4. References

Symptoms and diagnosis

People describe a creepy-crawly, pulling, or itchy feeling deep in the legs with an urge to move. To diagnose RLS, the urge must (1) start or worsen at rest, (2) ease with movement, and (3) be worse in the evening or night. It's often mistaken for insomnia. Problems with brain iron and dopamine signaling are thought to play a role.

Causes and treatment

If your ferritin is low, iron supplementation under a doctor's guidance can help a lot (see iron-deficiency anemia). Pregnancy, kidney disease, and some antihistamines and antidepressants can worsen it. The 2024 AASM guideline favors gabapentinoids and IV iron, and advises against routine dopamine agonists because of augmentation, where symptoms get worse over time. Cutting caffeine and alcohol and keeping a regular sleep schedule help.

This article is general health information and is not a substitute for diagnosis or treatment. If symptoms persist, see a doctor.

FAQ

Does massaging my legs help?
Massage, warm baths, and walking can bring short-term relief, but it's worth checking the underlying cause.
How is RLS different from leg cramps?
Cramps are painful muscle tightening; RLS is an uncomfortable urge to move without a locked muscle.

Sources reviewed: 2026-10-26

References

  1. Allen, R. P., et al. (2014). Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: Updated IRLSSG consensus criteria. Sleep Medicine, 15(8), 860–873.
  2. Winkelman, J. W., et al. (2024). Treatment of restless legs syndrome and periodic limb movement disorder: An AASM clinical practice guideline. Journal of Clinical Sleep Medicine.
  3. National Institute of Neurological Disorders and Stroke. Restless Legs Syndrome. NINDS.

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This article was last updated on October 26, 2026. It is based on widely recognized original works and textbooks; when citing it in a paper, please check the original sources listed in the references.