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Functional Dyspepsia

🩺 Nursing & Health By CampusDown Wiki Editorial Team Last updated Views 1
Functional dyspepsia is chronic indigestion with no structural cause found on testing. It's common, affecting roughly 1 in 10 adults worldwide.
Contents
  1. 1. Symptoms and causes
  2. 2. Testing and treatment
  3. 3. FAQ
  4. 4. References

Symptoms and causes

Under Rome IV, it's diagnosed when bothersome post-meal fullness, early satiety, or upper-belly pain or burning has lasted for at least three months (starting six months before) with no cause found on endoscopy. Contributors include a stomach that doesn't relax or empty normally, visceral hypersensitivity, and disrupted gut-brain signaling, often tied to stress.

Testing and treatment

People over about 60, or with red flags like weight loss, trouble swallowing, anemia, or black stools, need an endoscopy to rule out gastritis, ulcers, or cancer. Testing for and treating H. pylori can help. Options include acid suppressants, prokinetics, and low-dose neuromodulators, plus smaller, slower meals and less fatty food and alcohol.

This article is general health information and is not a substitute for diagnosis or treatment. If symptoms persist, see a doctor.

FAQ

Can functional dyspepsia turn into cancer?
No, but red-flag symptoms always need evaluation.
Is it okay to keep taking antacids?
Short-term is fine; if symptoms keep coming back for weeks, see a doctor to target the cause.

Sources reviewed: 2026-10-26

References

  1. Ford, A. C., Mahadeva, S., Carbone, M. F., Lacy, B. E., & Talley, N. J. (2020). Functional dyspepsia. The Lancet, 396(10263), 1689–1702.
  2. Stanghellini, V., et al. (2016). Gastroduodenal disorders. Gastroenterology, 150(6), 1380–1392. (Rome IV)
  3. Moayyedi, P., et al. (2017). ACG and CAG clinical guideline: Management of dyspepsia. American Journal of Gastroenterology, 112(7), 988–1013.

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This article was last updated on October 26, 2026. It is based on widely recognized original works and textbooks; when citing it in a paper, please check the original sources listed in the references.